Otro
Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?
Registro en:
Transactions of the Royal Society of Tropical Medicine and Hygiene. New York: Elsevier B.V., v. 101, n. 10, p. 1042-1044, 2007.
0035-9203
10.1016/j.trstmh.2007.04.011
WOS:000250027800016
Autor
Cavasini, Carlos Eugenio
de Mattos, Luiz Carlos
D'Almeida Couto, Alvaro Augusto
Bonini-Omingos, Claudia Regina
Valencia, Socrates Herrera
de Souza Neiras, Wanessa Christina
Alves, Renata Tome
Baptista Rossit, Andrea Regina
Castilho, Lilian
Dantas Machado, Ricardo Luiz
Resumen
We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both genotypic and non-genotypic screening tests. The Duffy blood group was genotyped by PCR/RFLP and phenotyped using a microtyping kit. We detected two homozygous FY*B-33 carriers infected by P vivax, whose circumsporozoite protein genotypes were VK210 and/or P. vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region. (C) 2007 Published by Elsevier Ltd on behalf of Royal Society of Tropical Medicine and Hygiene.