research article
Molecular profile in Paraguayan colorectal cancer patients, towards to a precision medicine strategy
Registro en:
10.1002/cam4.2191
Autor
Fleitas, Tania
Martinez Ciarpaglini, Carolina
Ayala, Josefina
Gauna, Cinthia
Denis, Rita Mabel Concepción
Yoffe, Ita
Sforza, Silvia
Martínez de Filártiga Filártiga, María Teresa
Pomata, Alicia
Ibarrola‐Villava, Maider
Arevshatyan, Sipan
Burriel, Verónica
Boscá, Diego
Pastor, Oscar
Ferrer, Ana
Carrasco, Francisca
Mongort, Cristina
Navarro, Samuel
Ribas, Gloria
Cervantes, Andres
Resumen
Somatic mutation analysis and evaluation of microsatellite instability (MSI) have become mandatory for selecting personalized therapy strategies for advanced colorectal cancer and are not available as routine methods in Paraguay. The aims of this study were to analyze the molecular profile as well as the microsatellite status in a series of advanced colorectal patients from two public hospitals from Paraguay, to introduce these methodologies in the routine practice to guide the therapeutic decisions. CONACYT – Consejo Nacional de Ciencia y Tecnología PROCIENCIA