Otro
Cytogenetic study of neoplastic and nonneoplastic cells of the skin
Registro en:
Cancer Genetics and Cytogenetics. New York: Elsevier B.V., v. 85, n. 1, p. 16-19, 1995.
0165-4608
10.1016/0165-4608(95)00128-X
WOS:A1995UC16000003
Autor
Pavarino, E. C.
Antonio, JR
Pozzeti, EMD
Larranaga, HJA
Tajara, E. H.
Resumen
We describe the cytogenetic study of six neoplastic and eight nonneoplastic skin samples from sun-exposed body sites or sites close to tumors. The cytogenetic findings revealed that chromosome rearrangements are common in sun-exposed normal skin, similar to the situation in cutaneous tumors, and suggest that such karyotypic abnormalities might be indicative of the genetic instability caused by specific mutations and resulting from carcinogenic exposure of the tissue.