Otro
Quantitative determination of cytotoxic friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography
Registro en:
Phytochemical Analysis. W Sussex: John Wiley & Sons Ltd, v. 13, n. 2, p. 75-78, 2002.
0958-0344
10.1002/pca.626
WOS:000174650500003
Autor
Buffa, W.
Corsino, J.
Bolzani, Vanderlan da Silva
Furlan, Maysa
Pereira, AMS
Franca, S. C.
Resumen
Five different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct accumulations of some friedo-nor-oleananes. A rapid, sensitive and reliable reverse-phase HPLC method (employing an external standard) was used for the determination of the cytotoxic triterpenoids, 20alpha-hydroxymaytenin, 22beta-hydroxymaytenin, maytenin, celastrol and pristimerin in each of the five types. Well resolved peaks with good detection response and linearity in the range 1.0-100 mug/mL were obtained. Copyright (C) 2002 John Wiley Sons, Ltd.