Artigo
The association between follicular size at time of spontaneous rupture and pregnancy rates in clomiphene citrate treated PCOS patients in coit cycles
Registro en:
Gynecological Endocrinology, v. 18, p. 1-4, 2015.
0951-3590
10.3109/09513590.2015.1006186
8499437381595614
Autor
Portocarrero, Carlos Sanchez [UNESP]
Gomes Sobrinho, David
Nakagawa, Hotomi
Silva, Adelino
Carvalho, Bruno
Sarkis, Nathália
Peraçoli, José Carlos [UNESP]
Cardoso, Maria Teresinha
Resumen
Objective: To investigate the follicular size at spontaneous rupture on pregnancy rate in patientswith polycystic ovary syndrome (PCOS) undergoing clomiphene citrate (CC) ovulation.Design: Cross-sectional study.Patients and methods: One hundred and four women with ovulatory cycles after use of CCfollowed by ultrasound to determine the follicle size at the time of rupture, which wassubsequently correlated with the occurrence of pregnancy or not in coit cycles.Results: In the group of follicular rupture at a mean diameter25 mm (n¼54), pregnancy ratewas 35.1% and when follicular rupture occurred at a mean diameter425 mm (n¼50), it was34% (p40.05). When different diameters at follicular rupture were randomly correlated with thepregnancy rate, there was no significant difference.Conclusion: Our data suggest that the occurrence of pregnancy after ovulation induction withCC in women with PCOS is not associated with follicle size at the time of rupture. Fundação de Ensino e Pesquisa em Ciências da Saúde (FEPECS) Hospital Regional do Gama, Departamento de Reprodução Humana Universidade Católica de Brasília, Departamento de Genética Universidade Estadual Paulista, Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Botucatu