Artigo
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats
Registro en:
Journal of Applied Oral Science, v. 18, n. 3, p. 237-243, 2010.
1678-7757
10.1590/S1678-77572010000300007
S1678-77572010000300007
S1678-77572010000300007.pdf
0047062193534190
4774447118127346
4068921369233125
Autor
Fernandes, Leandro Araujo
Martins, Thiago Marchi [UNESP]
Almeida, Juliano Milanezi de [UNESP]
Theodoro, Letícia Helena
Garcia, Valdir Gouveia [UNESP]
Resumen
OBJECTIVE: The aim of this study was to assess radiographically the effect of photodynamic therapy (PDT) as an adjunctive treatment to scaling and root planing (SRP) on induced periodontitis in dexamethasone-induced immunosuppressed rats. MATERIAL AND METHODS: The animals were divided into 2 groups: ND group (n=60): saline treatment; D group (n=60): dexamethasone treatment. In both ND and D groups, periodontal disease was induced by the placement of a ligature in the left first mandibular molar. After 7 days, ligature was removed and all animals received SRP, being divided according to the following treatments: SRP: saline and PDT: phenothiazinium dye (TBO) plus laser irradiation. Ten animals per treatment were killed at 7, 15 and 30 days. The distance between the cementoenamel junction and the height of the alveolar bone crest in the mesial surface of the mandibular left first molars was determined in millimeters in each radiograph. he radiographic values were analyzed statistically by ANOVA and Tukey's test at a p value <0.05. RESULTS: Intragroup radiographic assessment (ND and D groups) showed that there was statistically signifcant less bone loss in the animals treated with PDT in all experimental periods compared to those submitted to SRP. Intergroup radiographic analysis (ND and D groups) demonstrated that there was greater bone loss in the ND group treated with SRP compared to the D group treated with PDT at 7 and 30 days. CONCLUSION: PDT was an effective adjunctive treatment to SRP on induced periodontitis in dexamethasone-induced immunosuppressed rats. Department of Pathology and Clinical Dentistry, Federal University of Piauí, PI, Brazil Department of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, Brazil Department of Periodontics, University Center of Educational Foundation of Barretos, Barretos Dental School, Barretos, SP, Brazil Department of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, Brazil Universidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araçatuba, Aracatuba, Rua José Bonifário, 1193, Vila Mendonça, CEP 16015-050, SP, Brasil, Department of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, Brazil