Advances and challenges in paracoccidioidomycosis serology caused by Paracoccidioides species complex: an update

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorSilva, Julhiany de Fátima da [UNESP]
dc.creatorOliveira, Haroldo Cesar de [UNESP]
dc.creatorMarcos, Caroline Maria [UNESP]
dc.creatorAssato, Patricia Akemi [UNESP]
dc.creatorFusco-Almeida, Ana Marisa [UNESP]
dc.creatorMendes-Giannini, Maria José Soares [UNESP]
dc.date2015-12-07T15:34:33Z
dc.date2015-12-07T15:34:33Z
dc.date2015
dc.date.accessioned2023-09-12T07:34:07Z
dc.date.available2023-09-12T07:34:07Z
dc.identifierhttp://dx.doi.org/10.1016/j.diagmicrobio.2015.06.004
dc.identifierDiagnostic Microbiology And Infectious Disease, 2015.
dc.identifier1879-0070
dc.identifierhttp://hdl.handle.net/11449/131378
dc.identifier10.1016/j.diagmicrobio.2015.06.004
dc.identifier26494541
dc.identifier0000-0002-8059-0826
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8780659
dc.descriptionUnderstanding the possible methodologies for the rapid and inexpensive identification of fungal infections is essential for disease diagnosis, but there are some limitations. To help with this problem, serological methods that detect antigens or antibodies are widely used and are useful for the diagnosis of paracoccidioidomycosis (PCM) through the detection of gp43, which is the main antigen employed for the immunodiagnosis of this disease caused by Paracoccidioides brasiliensis. However, the use of gp43 has become restricted because it was recently found that this marker is not identified in the infections caused by Paracoccidioides lutzii. Therefore, it is necessary to identify new antigens in both species or antigens specific for P. lutzii to decrease the morbidity and/or mortality associated with PCM. This review provides a discussion of new diagnostic challenges after the recent discoveries regarding the taxonomy of the Paracoccidioides genus.
dc.descriptionFaculdade de Ciências Farmacêuticas de Araraquara, FCFAr, UNESP - Univ Estadual Paulista, Araraquara, Departamento de Análises Clínicas, SP, Brazil.
dc.descriptionFaculdade de Ciências Farmacêuticas de Araraquara, FCFAr, UNESP - Univ Estadual Paulista, Araraquara, Departamento de Análises Clínicas, SP, Brazil. Electronic address: giannini@fcfar.unesp.br.
dc.descriptionFaculdade de Ciências Farmacêuticas de Araraquara, FCFAr, UNESP - Univ Estadual Paulista, Araraquara, Departamento de Análises Clínicas, SP, Brazil.
dc.descriptionFaculdade de Ciências Farmacêuticas de Araraquara, FCFAr, UNESP - Univ Estadual Paulista, Araraquara, Departamento de Análises Clínicas, SP, Brazil. Electronic address: giannini@fcfar.unesp.br.
dc.languageeng
dc.publisherElsevier B. V.
dc.relationDiagnostic Microbiology And Infectious Disease
dc.rightsAcesso restrito
dc.sourcePubMed
dc.subjectImmunodiagnosis
dc.subjectParacoccidioides spp
dc.subjectParacoccidioidomycosis
dc.subjectSerology
dc.titleAdvances and challenges in paracoccidioidomycosis serology caused by Paracoccidioides species complex: an update
dc.typeArtigo


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