Artigo
Intrasellar chondroid chordoma: a case report
Registro en:
Isrn Endocrinology, v. 2011, 2011.
2090-4649
10.5402/2011/259392
PMC3317097.pdf
4880803690413862
2894975141895189
22500242
PMC3317097
Autor
Hirosawa, Renata M. [UNESP]
Santos, Antonio B. A.
França, Mariana M.
Fabris, Viciany Erique
Castro, Ana Valéria B
Zanini, Marco A.
Nunes, Vania S.
Resumen
Chordomas are tumors derived from cells that are remnants of the notochord, particularly from its proximal and distal extremes, they are mainly midline and represent approximately 1% of all malignant bone tumors and 0.1 to 0.2% of intracranial neoplasms. Chordomas involving the sellar region are rare. Herein, we describe a 57-year-old male patient presenting with a history of retro-orbital headache, progressive loss of vision, and clinical features of hypopituitarism, for over 2 months. During evaluation, the CT scan revealed a large contrast-enhancing intrasellar tumor with a 3.6-cm largest diameter. The patient underwent transsphenoidal partial resection of the tumor, and histological examination was consistent with the diagnosis of chondroid chordoma. Although chordomas are rare, they may be considered to constitute a differential diagnostic of pituitary adenomas, especially if a calcified intrasellar tumor with bone erosion is diagnosed. Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil. Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine of Botucatu, UNESP, 18618-970 Botucatu, SP, Brazil.