Cherubism: clinicoradiographic features and treatment

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorLima, Gabriela de Morais Gouvêa [UNESP]
dc.creatorAlmeida, Janete Dias [UNESP]
dc.creatorCabral, Luiz Antonio Guimarães [UNESP]
dc.date2015-12-07T15:30:01Z
dc.date2015-12-07T15:30:01Z
dc.date2010
dc.date.accessioned2023-09-12T07:25:32Z
dc.date.available2023-09-12T07:25:32Z
dc.identifierhttp://dx.doi.org/10.5037/jomr.2010.1202
dc.identifierJournal Of Oral & Maxillofacial Research, v. 1, n. 2, p. 1-8, 2010.
dc.identifier2029-283X
dc.identifierhttp://hdl.handle.net/11449/130895
dc.identifier10.5037/jomr.2010.1202
dc.identifierPMC3886048.pdf
dc.identifier9514297710569236
dc.identifier24421967
dc.identifierPMC3886048
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8780183
dc.descriptionCherubism is a congenital childhood disease of autosomal dominant inheritance. This disease is characterized by painless bilateral enlargement of the jaws, in which bone is replaced with fibrous tissue. The condition has sui generis clinical, radiographic and histological features, of which the clinician should be aware for a better differential diagnosis in the presence of a fibro-osseous lesion affecting the bones of the maxillomandibular complex. The purpose of present paper was to review the literature and to report the most important aspects of cherubism in order to facilitate the study of this disease. Literature was reviewed about cherubism, emphasizing the relevant clinicoradiographic features and treatment. Literature was selected through a search of PubMed and Scielo electronic databases. The keywords used for search were adolescent, cherubism, cherubism/physiopathology, cherubism/treatment, cherubism/radiography. A manual search of the reference lists of the identified articles and the authors' article files and recent reviews was conducted to identify additional publications. Those studies that described new features about cherubism were included in this review. In total 44 literature sources were obtained and reviewed. Studies that described new features about cherubism physiopathology, diagnostics and treatment were reviewed. Despite the exceptions, cherubism is a clinically well-characterized disease. In cases of a suspicion of cherubism, radiographic examination is essential since the clinical presentation, the location and distribution of the lesions may define the diagnosis. Histopathological examination is complementary. Nowadays, genetic tests should be used for final diagnosis of cherubism.
dc.descriptionPostgraduation Program in Oral Biopathology, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.
dc.descriptionDepartment of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.
dc.descriptionPostgraduation Program in Oral Biopathology, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.
dc.descriptionDepartment of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University - UNESP, São José dos Campos, São Paulo Brazil.
dc.format1-8
dc.languageeng
dc.publisherJournal Of Oral & Maxillofacial Research
dc.relationJournal Of Oral & Maxillofacial Research
dc.rightsAcesso aberto
dc.sourcePubMed
dc.subjectAdolescent
dc.subjectCherubism
dc.subjectJaw diseases
dc.titleCherubism: clinicoradiographic features and treatment
dc.typeArtigo


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