Artigo
Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs
Registro en:
International Journal of Cancer. New York: Wiley-liss, v. 50, n. 3, p. 341-344, 1992.
0020-7136
10.1002/ijc.2910500302
WOS:A1992HC03000001
2-s2.0-0026565666
Autor
Goloni-Bertollo, E. M. [UNESP]
Tajara, E. H. [UNESP]
Manzato, A. J. [UNESP]
Varella-Garcia, M.
Resumen
Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with 15 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents. Universidade Estadual Paulista (UNESP), Departamento de Biologia, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil Universidade Estadual Paulista (UNESP), Departamento Ciências da Computação e Estatística, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil Faculdade de Medicina de São José do Rio Preto, Departamento Ciências Biológicas, São José do Rio Presto,SP, Brazil Universidade Estadual Paulista (UNESP), Departamento de Biologia, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil Universidade Estadual Paulista (UNESP), Departamento Ciências da Computação e Estatística, IBILCE, CX POSTAL 136,BR-15055 São José do Rio Preto, SP, Brazil