Artigo
Bacterial cellulose biocomposites for guided tissue regeneration
Registro en:
Science Of Advanced Materials. Valencia: Amer Scientific Publishers, v. 6, n. 12, p. 2673-2678, 2014.
1947-2935
10.1166/sam.2014.1985
WOS:000348711900012
6443430122330366
Autor
Olyveira, Gabriel Molina de [UNESP]
Santos, Marcio Luiz dos [UNESP]
Manzine Costa, Ligia Maria
Daltro, Paula Braga [UNESP]
Basmaji, Pierre
Daltro, Gildysio de Cerqueira
Guastaldi, Antonio Carlos [UNESP]
Resumen
Bacterial cellulose (BC) has become established as a remarkably versatile biomaterial and can be used in a wide variety of scientific applications, especially for medical devices. In this work, the bacterial cellulose fermentation process is modified by the addition of chondroitin sulfate and hyaluronic acid (1% w/w) to the culture medium before the bacteria is inoculated. Besides, biomimetic precipitation of calcium phosphate of biological interest from simulated body fluid on bacterial cellulose was studied. Chondroitin sulfate and hyaluronic acid influences in bacterial cellulose were analyzed using transmission infrared spectroscopy (FTIR), XRD (X-ray diffraction) and scanning electron microscopy (SEM). FTIR analysis showed interaction between bacterial cellulose nanobiocomposites and calcium phosphate and XRD demonstrated amorphous calcium phosphate and calcium chloride on bacterial cellulose nanobiocomposites. SEM images confirmed incorporation of calcium phosphate in bacterial cellulose nanobiocomposites surface with different calcium phosphate particles morphology. Univ Estadual Paulista, Dept Phys Chem, BR-14800900 Sao Paulo, Brazil Univ Fed Abc, Dept Nanosci &Adv Mat, BR-09210170 Santo Andre, SP, Brazil Innovatecs Biotechnol Res &Dev, BR-13560042 Sao Carlos, SP, Brazil Univ Fed Bahia, Coll Hosp Complex Prof Edgard Santos COM HUPES, BR-40110910 Salvador, BA, Brazil Univ Estadual Paulista, Departamento de Física e Química, BR-14800900 Sao Paulo, Brazil