Reactionary dentinogenesis after applying restorative materials and bioactive dentin matrix molecules as liners in deep cavities prepared in nonhuman primate teeth

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorDuque, C.
dc.creatorHebling, J.
dc.creatorSmith, A. J.
dc.creatorGiro, EMA
dc.creatorOliveira, M. F.
dc.creatorCosta, CAD
dc.date2014-05-20T15:21:46Z
dc.date2016-10-25T17:55:18Z
dc.date2014-05-20T15:21:46Z
dc.date2016-10-25T17:55:18Z
dc.date2006-06-01
dc.date.accessioned2017-04-05T23:33:22Z
dc.date.available2017-04-05T23:33:22Z
dc.identifierJournal of Oral Rehabilitation. Oxford: Blackwell Publishing, v. 33, n. 6, p. 452-461, 2006.
dc.identifier0305-182X
dc.identifierhttp://hdl.handle.net/11449/32887
dc.identifierhttp://acervodigital.unesp.br/handle/11449/32887
dc.identifier10.1111/j.1365-2842.2005.01585.x
dc.identifierWOS:000237298900010
dc.identifierhttp://dx.doi.org/10.1111/j.1365-2842.2005.01585.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/877128
dc.descriptionObjective: the aim of this in vivo study was to evaluate the response of the pulp-dentin complex following application of resin-modified glass-ionomer cement, calcium hydroxide hard-setting cement and EDTA-soluble preparation of dentine matrix proteins (ESDP) in deep cavities prepared in non-human primate teeth. Methods: Eighteen deep Class V buccal cavities were prepared in premolars of four capuccin monkeys. In Groups 1 and 2, the cavity floor was lined with ESDP or a resin-modified glass-ionomer cement (Vitrebond - 3M ESPE), respectively. In Group 3 (control), the cavity was lined with a hard setting calcium hydroxide cement (Dycal - Dentsply). The cavities were subsequently filled with amalgam. After 6 months, the animals were sacrificed and the teeth were prepared for microscopic assessment. Six-micron thick serial sections were stained with H/E, Masson's trichrome and Brown & Brenn techniques. Results: No inflammatory pulpal response was observed for all experimental and control Groups. However, the amount of reactionary dentin deposition differed between groups in the rank order ESDP (Group 1) > calcium hydroxide (Group 3) > resin-modified glass-ionomer (Group 2). These differences were statistically significant. Conclusions: All materials were biocompatible when applied in deep cavities. ESDP stimulated higher deposition of reactionary dentin matrix than Vitrebond and Dycal.
dc.languageeng
dc.publisherBlackwell Publishing
dc.relationJournal of Oral Rehabilitation
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectpulp
dc.subjectdentine
dc.subjectbioactive molecules
dc.subjectdental materials
dc.subjectliners
dc.subjectdental cavities
dc.titleReactionary dentinogenesis after applying restorative materials and bioactive dentin matrix molecules as liners in deep cavities prepared in nonhuman primate teeth
dc.typeOtro


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