Otro
Bioactive pyrones and flavonoids from Cryptocarya ashersoniana seedlings
Registro en:
Arkivoc. Gainesville: Arkat Usa Inc., p. 127-136, 2004.
10.3998/ark.5550190.0005.616
WOS:000224153100016
WOS000224153100016.pdf
Autor
Ricardo, MAG
Andreo, M. A.
Cavalheiro, Alberto José
Gamboa, Ian Castro
Bolzani, Vanderlan da Silva
Silva, DHS
Resumen
The bioassay directed fractionation of the EtOH extract from leaves of Cryptocarya ashersoniana seedlings led to the isolation of two flavonol glucosides: iso-quercitrin and hyperin, which exhibited free radical scavenging activity towards DPPH (IC50 34.4 muM and 32.7 muM, respectively) and were compared to standard compounds rutin (IC50 27.0 muM) and catechin (IC50 41.4 muM). Investigation of extracts from the seedlings roots and stems afforded one antifungal styrylpyrone: goniothalamine, and two dihydropyrones: 6-propyl-5,6-dihydro-2-pyrone and the new 6-[(4'-ethyl-9'-oxabicyclo[3.3.1]non-6'-en-3'-yl)methyl]-5,6-dihydro-2H-pyran-2-one, which had its structure determined by detailed analysis of MS and NMR data, including 2D experiments.