Artigo
The genetic polymorphism of diabetic nephropathy
Registro en:
HealthMED, v. 8, n. 1, p. 109-111, 2014.
1840-2291
ISSN18402291-2014-08-01-109-111.pdf
6796970691432850
8456421836597174
Autor
Fonseca, Fernando L
Valenti, Vitor Engrácia [UNESP]
Antonio, Ana Marcia [UNESP]
Sousa, Fernando Henrique [UNESP]
Abreu, Luiz Carlos de
Resumen
Introduction: The Diabetic Nephropathy (DN) affects approximately 40% of patients diagnosed with DM is associated with increased mortality from cardiovascular phenomena and is considered the main cause of Chronic Renal Failure (CRF) in patients dialectics. Methods: Searches were performed on Medline, SciELO, Lilacs and Cochrane databases using the crossing between the key-words: “genetic polymorphism” and “diabetic nephropathy”. Results: The selected studies indicated that diabetic nephropathy is the leading cause of chronic renal failure, which significantly reduces the life expectancy of diabetics. Currently, some factors may have connection with DN. They are: genetic predisposition based on family history, hypertension, and cardiovascular events, quality of glycemic control and lipid levels and blood pressure and smoking. Conclusion: Studies constants are essential to add new elements in the literature for the definition (s) of factor (s) gene (s) specific (s) of diabetic nephropathy. Faculty of Sciences and Technology, UNESP, SP, Brazil, Faculty of Sciences, UNESP, SP, Brazil.