Preparation and antimicrobial activity of gelatin microparticles containing propolis against oral pathogens

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorBruschi, M. L.
dc.creatorLara, EHG
dc.creatorMartins, CHG
dc.creatorVinholis, AHC
dc.creatorCasemiro, L. A.
dc.creatorPanzeri, H.
dc.creatorGremiao, MPD
dc.date2014-05-20T15:20:21Z
dc.date2016-10-25T17:53:28Z
dc.date2014-05-20T15:20:21Z
dc.date2016-10-25T17:53:28Z
dc.date2006-01-01
dc.date.accessioned2017-04-05T23:25:26Z
dc.date.available2017-04-05T23:25:26Z
dc.identifierDrug Development and Industrial Pharmacy. Philadelphia: Taylor & Francis Inc., v. 32, n. 2, p. 229-238, 2006.
dc.identifier0363-9045
dc.identifierhttp://hdl.handle.net/11449/31678
dc.identifierhttp://acervodigital.unesp.br/handle/11449/31678
dc.identifier10.1080/03639040500466312
dc.identifierWOS:000235652200009
dc.identifierhttp://dx.doi.org/10.1080/03639040500466312
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/876172
dc.descriptionGelatin microparticles containing propolis ethanolic extractive solution were prepared by spray-drying technique. Particle,, with regular morphology, mean diameter ranging of 2.27 mu m to 2.48 mu m, and good entrapment efficiency for propolis were obtained. The in vitro antimicrobial activity of microparticles was evaluated against microorganisms of oral importance (Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus mitis, Streptococcus mutans, Streptococcus sobrinus, Candida albicans, and Lactobacillus casei). The utilized techniques were diffusion in agar and determination of minimum inhibitory concentration. The choice of the method to evaluate the antimicrobial activity of microparticles showed be very important. The microparticles displayed activity against all tested strains of similar way to the propolis, showing greater activity against the strains of E. salivarius, S. sanguinis, S. mitis, and C albicans.
dc.languageeng
dc.publisherTaylor & Francis Inc
dc.relationDrug Development and Industrial Pharmacy
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectpropolis
dc.subjectgelatin microparticles containing propolis
dc.subjectantimicrobial activity
dc.subjectoral pathogens
dc.titlePreparation and antimicrobial activity of gelatin microparticles containing propolis against oral pathogens
dc.typeOtro


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