Determination of 5-aminosalicylic acid in pharmaceutical formulations by square wave voltammetry at pencil graphite electrodes

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorUliana, Carolina V.
dc.creatorYamanaka, Hideko
dc.creatorGarbellini, Gustavo S.
dc.creatorSalazar-Banda, Giancarlo R.
dc.date2014-05-20T14:18:55Z
dc.date2016-10-25T17:40:48Z
dc.date2014-05-20T14:18:55Z
dc.date2016-10-25T17:40:48Z
dc.date2010-01-01
dc.date.accessioned2017-04-05T22:29:44Z
dc.date.available2017-04-05T22:29:44Z
dc.identifierQuímica Nova. Sociedade Brasileira de Química, v. 33, n. 4, p. 964-967, 2010.
dc.identifier0100-4042
dc.identifierhttp://hdl.handle.net/11449/25697
dc.identifierhttp://acervodigital.unesp.br/handle/11449/25697
dc.identifier10.1590/S0100-40422010000400036
dc.identifierS0100-40422010000400036
dc.identifierWOS:000278322500036
dc.identifierS0100-40422010000400036.pdf
dc.identifierhttp://dx.doi.org/10.1590/S0100-40422010000400036
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/870554
dc.descriptionAn analytical method for the determination of the anti-inflammatory drug 5-aminosalicylic acid (5-ASA) in pharmaceutical formulations using square wave voltammetry at pencil graphite electrodes was developed. After the optimization of the experimental conditions, calibration curves were obtained in the linear concentration range from 9.78 × 10-7 to 7.25 × 10-5 mol L-1 resulting in a limit of detection of 2.12 ± 0.05 x 10-8 mol L-1. Statistical tests showed that the concentrations of 5-ASA in commercial tablets and enemas obtained with the proposed voltammetric method agreed with HPLC values at a 95% confidence level.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherSociedade Brasileira de Química
dc.relationQuímica Nova
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject5-aminosalicylic acid
dc.subjectpharmaceutical formulations
dc.subjectpencil graphite electrode
dc.titleDetermination of 5-aminosalicylic acid in pharmaceutical formulations by square wave voltammetry at pencil graphite electrodes
dc.typeOtro


Este ítem pertenece a la siguiente institución