Phosphorylation of Histone H3S10 in Animal Chromosomes: Is There a Uniform Pattern?
Cytogenetic and Genome Research. Basel: Karger, v. 135, n. 2, p. 111-117, 2011.
Sotero-Caio, C. G.
de Souza, M. J.
Cabral-de-Mello, Diogo Cavalcanti
Brasileiro-Vidal, A. C.
Phosphorylation of serine 10 in histone H3 (H3S10ph) has been extensively analyzed and appears to be a conserved chromatin change associated with chromosome condensation in different eukaryotic organisms. In this work, we report the distribution of H3S10ph during meiosis in monocentric and holokinetic chromosomes of 6 insect species and in mitotic chromosomes of 7 mammalian species, aiming to investigate the labeling patterns in phylogenetically distant groups. The results indicated a very similar phosphorylation timing and distribution pattern among insects. The sex chromosomes of insects analyzed were always undercondensed and hypophosphorylated. Similarly, the micro chromosomes of the bug Pachylis aff pharaonis were also undercondensed and hypophosphorylated. Holokinetic chromosomes of bugs and monocentric chromosomes of grasshoppers and beetles displayed identical phosphorylation pattern in spite of the difference in the centromere type. Among mammals, a uniform chromosome phosphorylation was observed in marsupials, whereas bat chromosomes displayed a longitudinal banding pattern. These data indicate that, in general, the intensity of H3S10 phosphorylation in animal chromosomes is variable among the distinct chromosome types and associated with the degree of chromatin condensation at metaphase, but it may vary between different groups of animals. Copyright (C) 2011 S. Karger AG, BaselConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Showing items related by title, author, creator and subject.
Cavalli, L. R.; Cavaliéri, L. M B; Ribeiro, L. A.; Cavalli, I. J.; Silveira, R.; Rogatto, Silvia Regina
Universidade Federal do Paraná (UFPR); Universidade Estadual de Londrina (UEL); Universidade Estadual Paulista (UNESP); Hospital Nossa Senhora Das Gracas (1997-11-03)Chromosome analysis was performed on samples from 20 Brazilian patients with breast cancer. All the samples were from untreated patients who presented the clinical symptoms for months or years before surgical intervention. ...
Cytogenetic analysis of Epicauta atomaria (Meloidae) and Palembus dermestoides (Tenebrionidae) with Xyp sex determination system using standard staining, C-bands, NOR and synaptonemal complex microspreading techniques Almeida, Mara Cristina de; Zacaro, Adilson Ariza; Cella, Doralice Maria