Dissertação
Associação entre a força da preensão manual e depressão
Fecha
2022-09-28Autor
Mignoni, Ismael
Institución
Resumen
Previous studies demonstrate the association between Handgrip Strength (HGS) with
the risk of developing depression. However, the previous meta-analyses on the topic
took methodological decisions that may lead to biased estimates. The present study
aimed to evaluate the association between HGS and the incidence of depression
through a meta-analysis. Studies evaluating the association between HGS, assessed
using a hand-held dynamometer, and incident depression in adults were eligible for
the study. The study was registered in PROSPERO under the ID: CRD42022336752.
The databases used to search for included studies were: Embase, Psycinfo, Web Of
Science, Sportdiscus and Pubmed, until July 4, 2022. The search resulted in 1987
studies, of which eleven were included in the meta-analysis, accounting for 556,749
individuals, with an average age of 44.33 years old. Through a meta-analysis of
random effects, it was identified that people with higher HGS are 29% less likely to
develop incident depression when compared to those with lower HGS (OR = 0.702, CI
= 0.670-0.736, P < 0.001). Both the Begg-Mazumdar Kendall test (Tau = -0.090, P =
0.697) and the Egger's test (Intercept = -0.073, P = 0.877) and the visual analysis of
the funnel plot did not identify the presence of publication bias. According to the Failsafe N test, 331 studies with negative results are required to make the association not
statistically significant. The present findings support the notion that higher HGS is
prospectively associated with lower risk of incident depression.