Artigo
Mass Spectrometry Analysis of Protonated Marine Natural Product Seriniquinone
Fecha
2018Registro en:
Journal Of The Brazilian Chemical Society. Sao Paulo, v. 29, n. 5, p. 1162-1166, 2018.
0103-5053
S0103-50532018000501162.pdf
S0103-50532018000501162
10.21577/0103-5053.20180037
WOS:000427641700024
Autor
Silva, Rodrigo Moreira da
Guaratini, Thais
Jimenez, Paula Christine [UNIFESP]
Fenical, William
Costa-Lotufo, Leticia Veras
Vessecchi, Ricardo
Lopes, Norberto Peporine
Institución
Resumen
Seriniquinone is a natural quinone isolated from a rare marine bacterium of the genus Serinicoccus. This secondary metabolite has been shown to have anticancer properties, which has raised attention of the scientific community. In this short report, we present the first investigation of the gas-phase chemistry fragmentation reactions of seriniquinone in electrospray ionization tandem mass spectrometry (ESI-MS/MS), to be further applied in pharmacokinetics and metabolism studies. All the proposals herein were supported by computational chemistry.