Artigo
Retinal capillary hemangioma treatment by indocyanine green-mediated photothrombosis
Fecha
2003-03-01Registro en:
American Journal of Ophthalmology. New York: Elsevier B.V., v. 135, n. 3, p. 395-398, 2003.
0002-9394
10.1016/S0002-9394(02)01966-9
WOS:000181258100026
Autor
Costa, R. A.
Meirelles, R. L.
Cardillo, J. A.
Abrantes, M. L.
Farah, M. E.
Institución
Resumen
PURPOSE: To describe the clinical, angiographic and optical coherence tomography (OCT) findings of a patient with a large retinal capillary hemangioma who was treated by indocyanine green-mediated photothrombosis.DESIGN: Interventional case report.METHODS: An 18-year,old male patient was treated at a tertiary referral center with a novel laser-dye procedure that uses low-irradiance 810-nm laser and intravenous indocyanine green injection and was prospectively evaluated with fluorescein and indocyanine green angiography, as well as OCT.RESULTS: Vision improved from 20/125 to 20/32 + 1 at 1-year follow-up. Fundus photography showed marked reduction of a 3 disk diameters retinal capillary hemangioma. Both fluorescein and indocyanine green angiography demonstrated reduced tumor perfusion and narrowing of the lesion feeder and draining vessels, as early as 5 days after indocyanine green-mediated photothrombosis; OCT showed immediate decrease in retinal elevation and complete resolution of subretinal fluid within 2 months of treatment. Minimal laser,induced effects were noted in the vicinity of the tumor.CONCLUSIONS: Photothrombosis using low,intensity, 810-nm light to direct laser energy continuously at the tumor after intravenous indocyanine green infusion was effective in restoring macular architecture and improving vision in a patient with a large peripheral retinal capillary hemangioma by means of substantial occlusion of the tumor vasculature and resolution of subretinal fluid. (C) 2003 by Elsevier Science Inc. All rights reserved.