Otro
Short Report: Identification of Virulence-Associated Plasmids in Rhodococcus equi in Humans with and without Acquired Immunodeficiency Syndrome in Brazil
Registro en:
American Journal of Tropical Medicine and Hygiene. Mclean: Amer Soc Trop Med & Hygiene, v. 85, n. 3, p. 510-513, 2011.
0002-9637
10.4269/ajtmh.2011.10-0695
WOS:000294581400022
Autor
Ribeiro, Márcio Garcia
Takai, Shinji
de Vargas, Agueda Castagna
Mattos-Guaraldi, Ana Luiza
Ferreira Camello, Thereza Cristina
Ohno, Ryoko
Okano, Hajime
da Silva, Aristeu Vieira
Resumen
Virulence of Rhodococcus equi strains from 20 humans in Brazil was investigated by using a polymerase chain reaction to characterize isolates as virulent (VapA), intermediately virulent (VapB), and avirulent. Nine isolates were obtained from human immunodeficiency virus (HIV)-positive patients, six from HIV-negative patients, and five from patients of unknown status. Five isolates were VapB positive, four were VapA positive, and eleven were avirulent. Among the nine isolates from HIV-positive patients, five contained VapB plasmids and two contained VapA plasmids. Five VapB-positive isolates had the type 8 virulence plasmid. Eleven of the patients had a history of contact with livestock and/or a farm environment, and none had contact with pigs. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)