Otro
Ocular melanoma and mammary mucinous carcinoma in an African lion
Registro en:
Bmc Veterinary Research. London: Biomed Central Ltd., v. 8, p. 5, 2012.
1746-6148
10.1186/1746-6148-8-176
WOS:000312222400001
WOS000312222400001.pdf
Autor
Cagnini, Didier Quevedo
Salgado, Breno S.
Linardi, Juliana L.
Grandi, Fabrizio
Rocha, Rafael M.
Rocha, Noeme Sousa
Teixeira, Carlos Roberto
Del Piero, Fabio
Sequeira, Julio Lopes
Resumen
Background: Reports of neoplasms in Panthera species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.Case presentation: An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (Panthera leo). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.Conclusions: This is the first description of these tumor in African lions. Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)