Linfoma T lifoblástico: um relato de caso
T-Lymphoblastic lymphoma: a case report
| dc.contributor | Silva, Maria Cláudia Santos da | |
| dc.contributor | Walter, Laura Otto | |
| dc.contributor | Universidade Federal de Santa Catarina | |
| dc.creator | Silva, Mariana Dias da | |
| dc.date | 2022-03-25T11:14:59Z | |
| dc.date | 2022-03-25T11:14:59Z | |
| dc.date | 2022-03-16 | |
| dc.date.accessioned | 2023-09-02T10:12:35Z | |
| dc.date.available | 2023-09-02T10:12:35Z | |
| dc.identifier | https://repositorio.ufsc.br/handle/123456789/232884 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8590653 | |
| dc.description | TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Farmácia. | |
| dc.description | This study aims to report a clinical case of a female patient diagnosed with T-cell lymphoblastic lymphoma (T-LBL), a rare neoplasm of immature T-lymphoid lineage precursors that, according to the World Health Organisation (WHO) classification of Hematopoietic and Lymphoid Tissue Tumours of 2017, is grouped with T-cell acute lymphoblastic leukaemia (TALL) for presenting similar morphological and immunophenotypic characteristics, the main differences are the percentage of blasts present in the bone marrow (BM) and the evident clinical manifestations. Among the main characteristics, the patient had mediastinal mass, pleural effusion and cervical lymphadenopathy. Immunohistochemical analyses of cervical lymph node biopsy and immunophenotypic analyses of pleural fluid showed the presence of neoplastic cells that expressed cellular markers suggestive of T-LBL; the joint analysis of distinct biological samples by immunohistochemistry and immunophenotyping was the essential factor for the correct diagnosis of the disease and appropriate therapeutic decision. The treatment for the disease was based on intensive chemotherapy used for ALL, together with CNS prophylaxis. | |
| dc.format | 24 f. | |
| dc.format | application/pdf | |
| dc.format | application/pdf | |
| dc.language | en | |
| dc.publisher | Florianópolis, SC | |
| dc.rights | Open Access | |
| dc.subject | T-cell lymphoblastic lymphoma | |
| dc.subject | pleural fluid | |
| dc.subject | cervical lymph node | |
| dc.subject | flow cytometry | |
| dc.subject | immunohistochemistry | |
| dc.title | Linfoma T lifoblástico: um relato de caso | |
| dc.title | T-Lymphoblastic lymphoma: a case report | |
| dc.type | Article |