dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorVerissimo, Lourena Mafra
dc.creatorAgnez Lima, Lucymara Fassarela
dc.creatorMonte Egito, Lucila Carmem
dc.creatorOliveira, Anselmo Gomes de
dc.creatorTabosa do Egito, E. Socrates
dc.date2014-05-20T13:24:51Z
dc.date2016-10-25T16:45:30Z
dc.date2014-05-20T13:24:51Z
dc.date2016-10-25T16:45:30Z
dc.date2010-06-01
dc.date.accessioned2017-04-05T20:01:28Z
dc.date.available2017-04-05T20:01:28Z
dc.identifierJournal of Drug Targeting. London: Informa Healthcare, v. 18, n. 5, p. 333-342, 2010.
dc.identifier1061-186X
dc.identifierhttp://hdl.handle.net/11449/7818
dc.identifierhttp://acervodigital.unesp.br/handle/11449/7818
dc.identifier10.3109/10611860903434019
dc.identifierWOS:000277364900001
dc.identifierhttp://dx.doi.org/10.3109/10611860903434019
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/856354
dc.descriptionThe concept of gene therapy involves the experimental transfer of a therapeutic gene into an individual's cells and tissues to replace an abnormal gene aiming to treat a disease, or to use the gene to treat a disease just like a medicine, improving the clinical status of a patient. The achievement of a foreigner nucleic acid into a population of cells requires its transfer to the target. Therefore, it is essential to create carriers (vectors) that transfer and protect the nucleic acid until it reaches the target. The obvious disadvantages of the use of viral vectors have directed the research for the development of a nonviral organized system such as emulsions. In fact, recently, there has been an increase of interest in its use in biotechnology as a nonviral vector for gene therapy. This review focuses on the progress of cationic emulsions and the improvement of the formulations, as a potential delivery system for gene therapy.</.
dc.languageeng
dc.publisherInforma Healthcare
dc.relationJournal of Drug Targeting
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCationic emulsions
dc.subjectgene transfection
dc.subjectgene therapy
dc.subjectcarrier systems
dc.subjectdelivery systems
dc.titlePharmaceutical emulsions: a new approach for gene therapy
dc.typeOtro


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