Article
Green ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent?
Registro en:
Sepulveda B, Benites D, Albornoz L, Simirgiotis M, Castro O, Garcia-Beltran O, Areche C. Green ultrasound-assisted extraction of lichen substances from Hypotrachyna cirrhata. Ethyl lactate, a better extracting agent than methanol toxic organic solvent? Nat Prod Res. 2021 Jul 28:1-5. doi: 10.1080/14786419.2021.1956922. Epub ahead of print. PMID: 34319194.
1478-6419
Autor
Sepulveda, Beatriz
Benites, Derin
Albornoz, Laura
Simirgiotis, Mario
Castro, Olivio
Garcia-Beltran, Olimpo
Areche, Carlos
Institución
Resumen
For the first time, we report a green extraction of lichen substances assisted by high power ultrasounds from Hypotrachyna cirrhata using ethyl lactate. This sustainable alternative was comparable, both in isolation and detection of lichen substances, to methanol. In the metabolomic analysis, a total of 77 lichen substances were detected comprising depsides, depsidones, dibenzofurans, organic acids, and lipids. Although the UHPLC/ESI/MS profiles were similar, the antioxidant activity was higher for the ethyl lactate extract. Ethyl lactate can replace toxic organic solvents, such as methanol, in order to provide more sustainable green chemistry methods. Universidad de Ibagu?