The aim of this chapter is to describe climate characteristics since the Anthropocene inception and to assess expected climate changes in Patagonia, with emphasis on coastal areas. The climate in Patagonia has warmed up since 1950, and this trend is expected to continue in the future. However, the situation is slightly different in coastal areas where temperature trends are weaker and even negative in several locations, while future projections indicate an increase in mean temperature. Although precipitation in coastal areas is scarce and there is a large interannual variability, recent trends indicate a slight decrease, and future projections show wetter conditions in coastal areas north of 44°S and dryer conditions in southern regions. Additionally, precipitation extreme events are expected to increase in the future. Regarding wind intensity, there is a clear negative trend for most of the coastal areas except for the southern tip, and this pattern will continue during the twenty-first century. Trends and projections in the climate of coastal areas could be related with changes in the large-scale circulation variability patterns. The most relevant is associated with the impact of the significant trend toward positive polarity of the Southern Annular Mode during the second half of the twentieth century.Fil: Pessacg, Natalia Liz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico para el Estudio de los Ecosistemas Continentales; ArgentinaFil: Blazquez, Josefina. Universidad Nacional de La Plata. Facultad de Ciencias Astronómicas y Geofísicas; ArgentinaFil: Lancelotti, Julio Lucio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico para el Estudio de los Ecosistemas Continentales; ArgentinaFil: Solman, Silvina Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; Argentina