Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMarcondes, Jackson
dc.creatorHansen, Ekkehard
dc.date2014-05-20T13:17:34Z
dc.date2014-05-20T13:17:34Z
dc.date2008-12-01
dc.date.accessioned2017-04-05T19:38:31Z
dc.date.available2017-04-05T19:38:31Z
dc.identifierBrazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 12, n. 6, p. 469-471, 2008.
dc.identifier1413-8670
dc.identifierhttp://hdl.handle.net/11449/3994
dc.identifier10.1590/S1413-86702008000600004
dc.identifierS1413-86702008000600004
dc.identifierWOS:000264200300004
dc.identifierS1413-86702008000600004.pdf
dc.identifierhttp://dx.doi.org/10.1590/S1413-86702008000600004
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/853441
dc.descriptionThe obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety Vitória de Verão genetically modified.
dc.languageeng
dc.publisherBrazilian Society of Infectious Diseases
dc.relationBrazilian Journal of Infectious Diseases
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEdible vaccine
dc.subjectHepatitis B
dc.subjectOral immunization
dc.subjectRecombinant antigen
dc.subjectTransgenic plants
dc.titleTransgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg
dc.typeOtro


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