Clinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorAquino, Lúcia Padilha Cury Thomaz de
dc.creatorMachado, Rosangela Zacarias
dc.creatorAlessi, Antônio Carlos
dc.creatorMarques, Luiz Carlos
dc.creatorCastro, Márcio Botelho de
dc.creatorMalheiros, Euclides Braga
dc.date2014-05-20T13:15:58Z
dc.date2014-05-20T13:15:58Z
dc.date1999-03-01
dc.date.accessioned2017-04-05T19:33:13Z
dc.date.available2017-04-05T19:33:13Z
dc.identifierMemórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 94, n. 2, p. 255-260, 1999.
dc.identifier0074-0276
dc.identifierhttp://hdl.handle.net/11449/2965
dc.identifier10.1590/S0074-02761999000200025
dc.identifierS0074-02761999000200025
dc.identifierS0074-02761999000200025.pdf
dc.identifierhttp://dx.doi.org/10.1590/S0074-02761999000200025
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/852769
dc.descriptionThis research investigated the pattern of antibody response by means of enzyme linked immunosorbent assay (Elisa) and indirect fluorescent antibody test (IFAT) through the course of experimental Trypanosoma evansi infection in dogs. Clinical and parasitological features were also studied. The average prepatent period was 11.2 days and parasitaemia showed an undulating course. Biometrical study of parasites revealed a mean total length of 21.68mm. The disease was characterized by intermittent fever closely related to the degree of parasitaemia and main clinical signs consisted of pallor of mucous membrane, edema, progressive emaciation and enlargement of palpable lymph nodes. Diagnostic antibody was detected within 12 to 15 days and 15 to 19 days of infection by IFAT and Elisa, respectively. High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia
dc.languageeng
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúde
dc.relationMemórias do Instituto Oswaldo Cruz
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTrypanosoma evansi
dc.subjectDog
dc.subjectbiometry
dc.subjectELISA
dc.subjectinmunofluorescent antibody test
dc.subjectclinical features
dc.titleClinical, parasitological and immunological aspects of experimental infection with Trypanosoma evansi in dogs
dc.typeOtro


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