Serological evidence of hantavirus infection in apparently healthy people from rural and slum communities in southern Chile

dc.creatorMuñoz-Zanzi, Claudia
dc.creatorSaavedra, Farides
dc.creatorOtth, Carola
dc.creatorDomancich, Ljubica
dc.creatorHott, Melissa
dc.creatorPadula, Paula
dc.date2021-01-26T15:48:04Z
dc.date2021-01-26T15:48:04Z
dc.date2015-04-17
dc.date.accessioned2023-08-29T20:09:12Z
dc.date.available2023-08-29T20:09:12Z
dc.identifier1999-4915
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/2266
dc.identifierhttps://www.mdpi.com/1999-4915/7/4/2006
dc.identifier10.3390/v7042006
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520564
dc.descriptionFil: Muñoz-Zanzi, Claudia. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota; Estados Unidos.
dc.descriptionFil: Saavedra, Farides. Institute of Clinical Microbiology, Austral University of Chile; Chile.
dc.descriptionFil: Otth, Carola. Institute of Clinical Microbiology, Austral University of Chile; Chile.
dc.descriptionFil: Domancich, Ljubica. Institute of Clinical Microbiology, Austral University of Chile; Chile.
dc.descriptionFil: Hott, Melissa. Institute of Clinical Microbiology, Austral University of Chile; Chile.
dc.descriptionFil: Padula, Paula. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionHantavirus disease in America has been recognizable because of its rapid progression in clinical cases, occurrence in previously healthy young adults, and high case fatality rate. Hantavirus disease has been proposed now to define the diversity of clinical manifestations. Since 1995, a total of 902 cases of hantavirus pulmonary syndrome have been reported in Chile, caused by Andes virus (ANDV), with overall fatality of 32%. This report describes the sero-epidemiology of hantavirus in apparently healthy people in rural and urban slum communities from southern Chile. Ten of 934 samples yielded a positive result resulting in a seroprevalence of 1.07% (95% confidence intervals: 0.05%-2.0%). A higher proportion of positive samples was found among individuals from rural villages (1.3%) and slums (1.5%) compared with farms (0.5%). Seropositivity was associated with age (p = 0.011), low education level (p = 0.006) and occupations linked to the household (homemaker, retired, or student) (p = 0.016). No evidence of infection was found in 38 sigmodontinae rodents trapped in the peri-domestic environment. Our findings highlight that exposure risk was associated with less documented risk factors, such as women in slum and rural villages, and the occurrence of infection that may have presented as flu-like illness that did not require medical attention or was misdiagnosed.
dc.formatpdf
dc.languageen
dc.publisherMDPI
dc.relationViruses
dc.rightsopen
dc.sourceViruses 2015; 7(4):2006-13
dc.subjectHantavirus
dc.subjectChile
dc.titleSerological evidence of hantavirus infection in apparently healthy people from rural and slum communities in southern Chile
dc.typeArtículo


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