Pandemic influenza A/H1N1 2009 antibodies in the metropolitan area of Buenos Aires in Argentina

dc.creatorLabato, Mariana I
dc.creatorContrini, María M
dc.creatorLazzarini, Daniela
dc.creatorCampos, Ana
dc.creatorGauna, María L
dc.creatorClaros, Ronald
dc.creatorLopez, Eduardo L.
dc.creatorSavy, Vilma L.
dc.creatorLuna, Carlos M
dc.date2021-01-22T19:28:52Z
dc.date2021-01-22T19:28:52Z
dc.date2014-02
dc.date.accessioned2023-08-29T20:09:05Z
dc.date.available2023-08-29T20:09:05Z
dc.identifierhttps://www.ijidonline.com/article/S1201-9712(13)00313-5/fulltext
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/2230
dc.identifier10.1016/j.ijid.2013.09.021
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520497
dc.descriptionFil: Labato, Mariana I. Universidad de Buenos Aires. Hospital de Clínicas "José de San Martín", Buenos Aires; Argentina.
dc.descriptionFil: Contrini, María M. Hospital de Niños "Ricardo Gutiérrez", Buenos Aires; Argentina.
dc.descriptionFil: Lazzarini, Daniela. Hospital de Niños "Ricardo Gutiérrez", Buenos Aires; Argentina.
dc.descriptionFil: Campos, Ana María. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionFil: Gauna, María L. Universidad de Buenos Aires. Hospital de Clínicas "José de San Martín", Buenos Aires; Argentina.
dc.descriptionFil: Claros, Ronald. Universidad de Buenos Aires. Hospital de Clínicas "José de San Martín", Buenos Aires; Argentina.
dc.descriptionFil: López, Eduardo L. Hospital de Niños "Ricardo Gutiérrez", Buenos Aires; Argentina.
dc.descriptionFil: Savy, Vilma L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
dc.descriptionFil: Luna, Carlos M. Universidad de Buenos Aires. Hospital de Clínicas "José de San Martín", Buenos Aires; Argentina.
dc.descriptionObjective To estimate the infection prevalence in Buenos Aires during the outbreak of pandemic influenza A/H1N1 2009 virus (A(H1N1)pdm09). Methods A(H1N1)pdm09-specific antibodies were measured by hemagglutination inhibition assay in human serum samples collected 6 months after the outbreak and before the introduction of the A(H1N1)pdm09 vaccine in Argentina. Baseline levels of cross-reactive antibodies to A(H1N1)pdm09 were determined by testing 162 serum samples collected before 2009. Results The overall seroprevalence of A(H1N1)pdm09 in 150 children and 427 adults was 28.9% (95% confidence interval (CI) 25–33%), with a 58.0% prevalence in children <19 years of age and an 18.7% prevalence in adults ≥19 years of age (p < 0.001). The prevalence was 43.5% in children <5 years old and 60.6% among children aged 5–18 years. The prevalence in adults declined with increasing age: 24.9% in 19–39-year-olds, 9.7% in 40–59-year-olds, and 8.1% in those ≥60 years old. The prevalence of specific A(H1N1)pdm09 antibodies was higher compared with the baseline in children (p = 0.014), adolescents (p < 0.001), and adults <40 years old (p = 0.017). Seroprevalence in health care workers was not different from the rest of the population (13.6% vs. 19.3%, respectively; p = 0.421). Conclusions The prevalence of specific A(H1N1)pdm09 antibodies was high at 28.9%. The highest prevalence was observed in children, adolescents, and young adults.
dc.formatpdf
dc.languageen
dc.relationInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
dc.rightsopen
dc.sourceInternational journal of infectious diseases 2014;19:20-25
dc.subjectVirus de la Influenza A
dc.subjectPrevalencia
dc.subjectEstudios Seroepidemiológicos
dc.titlePandemic influenza A/H1N1 2009 antibodies in the metropolitan area of Buenos Aires in Argentina
dc.typeArtículo


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