Genetic diversity and virulence potential of shiga toxin-producing Escherichia coli O113:H21 strains isolated from clinical, environmental, and food sources

dc.creatorFeng, Peter C. H.
dc.creatorDelannoy, Sabine
dc.creatorLacher, David W
dc.creatorDos Santos, Luis Fernando
dc.creatorBeutin, Lothar
dc.creatorFach, Patrick
dc.creatorRivas, Marta
dc.creatorHartland, Elizabeth L
dc.creatorPaton, Adrienne W
dc.creatorGuth, Beatriz E C
dc.date2020-12-23T15:40:14Z
dc.date2020-12-23T15:40:14Z
dc.date2014-08
dc.date.accessioned2023-08-29T20:08:10Z
dc.date.available2023-08-29T20:08:10Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1986
dc.identifier10.1128/AEM.01182-14
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520030
dc.descriptionFil: Feng, Peter C H. Food and Drug Administration. Division of Microbiology; Estados Unidos.
dc.descriptionFil: Delannoy, Sabine. French Agency for Food, Environmental, and Occupational Health and Safety. Laboratory for Food Safety; Francia.
dc.descriptionFil: Lacher, David W. Food and Drug Administration. Division of Molecular Biology; Estados Unidos.
dc.descriptionFil: Dos Santos, Luis Fernando. Universidade Federal de São Paulo. Department of Microbiology, Immunology and Parasitology; Brasil.
dc.descriptionFil: Beutin, Lothar. Federal Institute for Risk Assessment. National Reference Laboratory for Escherichia coli; Alemania.
dc.descriptionFil: Fach, Patrick. French Agency for Food, Environmental, and Occupational Health and Safety. Laboratory for Food Safety; Francia.
dc.descriptionFil: Rivas, Marta. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Servicio Fisiopatogenia; Argentina.
dc.descriptionFil: Hartland, Elizabeth L. University of Melbourne at the Peter Doherty Institute for Infection and Immunity. Department of Microbiology and Immunology; Australia.
dc.descriptionFil: Paton, Adrienne W. University of Adelaide. School of Molecular and Biomedical Science. Research Centre for Infectious Diseases; Australia.
dc.descriptionFil: Guth, Beatriz E C. Universidade Federal de São Paulo. Department of Microbiology, Immunology and Parasitology; Brasil.
dc.descriptionShiga toxin-producing Escherichia coli strains of serotype O113:H21 have caused severe human diseases, but they are unusual in that they do not produce adherence factors coded by the locus of enterocyte effacement. Here, a PCR microarray was used to characterize 65 O113:H21 strains isolated from the environment, food, and clinical infections from various countries. In comparison to the pathogenic strains that were implicated in hemolytic-uremic syndrome in Australia, there were no clear differences between the pathogens and the environmental strains with respect to the 41 genetic markers tested. Furthermore, all of the strains carried only Shiga toxin subtypes associated with human infections, suggesting that the environmental strains have the potential to cause disease. Most of the O113:H21 strains were closely related and belonged in the same clonal group (ST-223), but CRISPR analysis showed a great degree of genetic diversity among the O113:H21 strains.
dc.formatpdf
dc.languageen
dc.publisherAmerican Society for Microbiology
dc.relation#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.relationdatasets
dc.relationApplied and environmental microbiology
dc.rightsopen
dc.sourceApplied and Environmental Microbiology 2014; 80(15):4757-4763
dc.subjectAnimales
dc.subjectBovinos
dc.subjectPerros
dc.subjectInfecciones por Escherichia coli
dc.subjectProteínas de Escherichia coli
dc.subjectHeces
dc.subjectMicrobiología de Alimentos
dc.subjectCabras
dc.subjectHumanos
dc.subjectCarne
dc.subjectDatos de Secuencia Molecular
dc.subjectFilogenia
dc.subjectToxina Shiga
dc.subjectEscherichia coli Shiga-Toxigénica
dc.subjectFactores de Virulencia
dc.subjectMicrobiología Ambiental
dc.subjectVariación Genética
dc.titleGenetic diversity and virulence potential of shiga toxin-producing Escherichia coli O113:H21 strains isolated from clinical, environmental, and food sources
dc.typeArtículo


Este ítem pertenece a la siguiente institución