Natural Snake Venom Inhibitors and their Pharmaceutical Uses: Challenges and Possibilities

dc.creatorSaavedra, Soledad Lorena
dc.creatorÁvila, Lucía
dc.creatorGiudicessi, Silvana Laura
dc.creatorAlbericio, Fernando
dc.creatorCamperi, Silvia Andrea
dc.creatorCascone, Osvaldo
dc.creatorMartinez-Ceron, Maria Camila
dc.date2020-12-23T15:38:52Z
dc.date2020-12-23T15:38:52Z
dc.date2018
dc.date.accessioned2023-08-29T20:08:08Z
dc.date.available2023-08-29T20:08:08Z
dc.identifier1873-4286
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1981
dc.identifier10.2174/1381612824666180223172854
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8520020
dc.descriptionFil: Saavedra, Soledad Lorena. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Biotecnología; Argentina.
dc.descriptionFil: Ávila, Lucía. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Producción de Biológicos; Argentina.
dc.descriptionFil: Giudicessi, Silvana Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Biotecnología; Argentina.
dc.descriptionFil: Albericio, Fernando. University of Barcelona. Department of Organic Chemistry; España.
dc.descriptionFil: Camperi, Silvia Andrea. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Biotecnología; Argentina.
dc.descriptionFil: Cascone, Osvaldo. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Biotecnología; Argentina.
dc.descriptionFil: Martinez-Ceron, Maria Camila. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Cátedra de Biotecnología; Argentina.
dc.descriptionNowadays, treatment with specific antivenins is considered the only cure for snakebites accidents. However, access to antivenom obstructs the successful implementation of the World Health Organization international guidelines. In the last few years, natural organic compounds, peptides, and proteins with the ability to inhibit snake toxins and obtained from different sources such as plant extracts and animal blood have been proposed as antivenoms. In this work, we will focus on the inhibitors of the main venom toxins, phospholipases A2 and metalloproteinases, and their application as novel antivenoms.
dc.formatpdf
dc.languageen
dc.relationCurrent Pharmaceutical Design
dc.rightsnone
dc.sourceCurrent Pharmaceutical Design 2018;24(16):1737-1747
dc.subjectMetaloproteasas
dc.subjectPéptidos
dc.subjectFosfolipasas A2
dc.subjectExtractos Vegetales
dc.subjectProteínas
dc.titleNatural Snake Venom Inhibitors and their Pharmaceutical Uses: Challenges and Possibilities
dc.typeArtículo


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