Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT)

dc.creatorMarin-Neto, José Antônio
dc.creatorRassi, Anis
dc.creatorMorillo, Carlos A
dc.creatorAvezum, Álvaro
dc.creatorConnolly, Stuart J
dc.creatorSosa-Estani, Sergio
dc.creatorRosas, Fernando
dc.creatorYusuf, Salim
dc.date2020-12-18T15:59:23Z
dc.date2020-12-18T15:59:23Z
dc.date2008-07
dc.date.accessioned2023-08-29T20:08:00Z
dc.date.available2023-08-29T20:08:00Z
dc.identifier0002-8703
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1939
dc.identifier10.1016/j.ahj.2008.04.001
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519941
dc.descriptionFil: Marin-Neto, José Antônio. Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirão Preto, Sao Paulo; Brasil.
dc.descriptionFil: Rassi, Anis. Anis Rassi Hospital, Goiania; Brasil.
dc.descriptionFil: Morillo, Carlos A. McMaster University, Population Health Research Institute HGH-McMaster Clinic, East Hamilton, Ontario; Canada.
dc.descriptionFil: Avezum, Álvaro. Instituto Dante Pazzanese de Cardiologia, Sao Paulo; Brasil.
dc.descriptionFil: Connolly, Stuart J. McMaster University, Population Health Research Institute HGH-McMaster Clinic, East Hamilton, Ontario; Canada.
dc.descriptionFil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Centro Nacional de Diagnóstico e Investigación en Endemo-Epidemias; Argentina.
dc.descriptionFil: Rosas, Fernando. Clinica A. Saio, Bogota; Colombia.
dc.descriptionFil: Yusuf, Salim. McMaster University, Population Health Research Institute HGH-McMaster Clinic, East Hamilton, Ontario; Canada.
dc.descriptionBenznidazole is effective for treating acute and chronic (recently acquired) Trypanosoma cruzi infection (Chagas' disease). Recent data indicate that parasite persistence plays a pivotal role in the pathogenesis of chronic Chagas' cardiomyopathy. However, the efficacy of trypanocidal therapy in preventing clinical complications in patients with preexisting cardiac disease is unknown.
dc.languageen
dc.publisherElsevier
dc.relationAmerican Heart Journal
dc.rightsnone
dc.sourceAmerican Heart Journal 2008 Jul;156(1):37-43.
dc.subjectCardiomiopatía Chagásica
dc.subjectTrypanosoma cruzi
dc.titleRationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT)
dc.typeArtículo


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