| dc.creator | Cardoni, Rita L. | |
| dc.creator | García, Miriam Martin | |
| dc.creator | De Rissio, Ana María | |
| dc.date | 2020-12-16T23:39:40Z | |
| dc.date | 2020-12-16T23:39:40Z | |
| dc.date | 2004-03 | |
| dc.date.accessioned | 2023-08-29T20:07:58Z | |
| dc.date.available | 2023-08-29T20:07:58Z | |
| dc.identifier | 0001-706X | |
| dc.identifier | http://sgc.anlis.gob.ar/handle/123456789/1922 | |
| dc.identifier | 10.1016/j.actatropica.2003.09.020 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8519930 | |
| dc.description | Fil: Cardoni, Rita L. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | |
| dc.description | Fil: García, Miriam Martin. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | |
| dc.description | Fil: De Rissio, Ana María. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina. | |
| dc.description | Mother-to-child transmission of intracellular parasites could be related to the production of immunoregulatory cytokines. The levels of gamma interferon (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) and lnterleukin (IL)-10 were evaluated during pregnancy in sera of women chronically infected with Trypanosoma cruzi that delivered infected or non-infected children. The levels of IL-10 increased in both, women only pregnant and only infected, compared to non-infected non-pregnant women. However, in pregnant women chronically infected with T. cruzi, IL-10 did not increase significantly, neither in the mothers of infected nor in the mothers of non-infected children. The levels of the inflammatory cytokine TNF-alpha were not affected in normal pregnancy but increased in the infected mothers of non-infected children. The levels of IFN-gamma did not increase in the groups studied, indicating that the production of this pro-inflammatory cytokine was controlled, even when the levels of IL-10 did not increase, as in pregnant women chronically infected with T. cruzi. | |
| dc.language | en | |
| dc.publisher | Elsevier | |
| dc.relation | Acta tropica | |
| dc.rights | none | |
| dc.subject | Trypanosoma cruzi | |
| dc.subject | Mujeres Embarazadas | |
| dc.title | Proinflammatory and anti-inflammatory cytokines in pregnant women chronically infected with Trypanosoma cruzi | |
| dc.type | Artículo | |
