In vitro infection by different strains of Paracoccidioides brasiliensis

dc.creatorCanteros, Cristina Elena
dc.creatorSoria, Marcelo
dc.creatorRivas, María Cristina
dc.creatorPérez, Celeste Luján
dc.creatorTous, Mónica
dc.creatorLee, William
dc.creatorRodero, Laura
dc.creatorDavel, Graciela Odelsia
dc.date2020-12-04T09:08:19Z
dc.date2020-12-04T09:08:19Z
dc.date2000
dc.date.accessioned2023-08-29T20:07:31Z
dc.date.available2023-08-29T20:07:31Z
dc.identifier0325-7541
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1816
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519702
dc.descriptionFil: Canteros, C. E. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionFil: Davel, Graciela Odelsia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Micología; Argentina.
dc.descriptionWe analyzed the in vitro infection process by P. brasiliensis and the effect of extracellular factor(s) produced on monolayers of mammalian Vero cell lines. The yeast phase of four strains was studied: B339 (avirulent or slightly virulent), U, (intermediate virulence), 93745 and 63265 (both highly virulent). Strains of intermediate and high virulence had higher adherence at first contact (about 16%). Strain B339 had a slower adherence at first contact (8%) than the others during the same period. The production of extracellular proteases, soluble extracellular factor(s) and extracellular antigen gP43 showed no correlation with the in vitro physiopathogenicity of the analyzed strains. We demonstrate that the Vero model presented in this paper is a suitable system to study infection and virulence in vitro. We are currently assessing its usefulness as a tool for the analysis of the interaction between pathogen, host and antifungal agents.
dc.formatpdf
dc.languagees
dc.relationRevista Argentina de microbiologia
dc.rightsnone
dc.sourceRevista Argentina de Microbiología 2000;32(3):116-22
dc.subjectAnimales
dc.subjectChlorocebus aethiops
dc.subjectMedios de Cultivo
dc.subjectProteínas Fúngicas
dc.subjectGlicoproteínas
dc.subjectMicología
dc.subjectOligosacáridos
dc.subjectParacoccidioides
dc.subjectEspecificidad de la Especie
dc.subjectCélulas Vero
dc.subjectVirulencia
dc.subjectAntígenos Fúngicos
dc.titleIn vitro infection by different strains of Paracoccidioides brasiliensis
dc.typeArtículo


Este ítem pertenece a la siguiente institución