Artículo
AFLP analysis reveals high genetic diversity but low population structure in Coccidioides posadasii isolates from Mexico and Argentina
Registro en:
1471-2334
10.1186/1471-2334-13-411
Autor
Duarte-Escalante, Esperanza
Zúñiga, Gerardo
Frias-De Leon, Maria Guadalupe
Canteros, Cristina
Castañon-Olivares, Laura R.
Reyes-Montes, María del Rocío
Resumen
Fil: Duarte-Escalante, Esperanza. Universidad Nacional Autónoma de México (UNAM). Facultad de Medicina. Departamento de Microbiología y Parasitología; México. Fil: Zúñiga, Gerardo. Instituto Politécnico Nacional. Departamento de Zoología. Escuela Nacional de Ciencias Biológicas; México. Fil: Frías-De-León, María Guadalupe. Hospital Juárez de México. División de Investigación; México. Fil: Canteros, Cristina. ANLIS Dr.C.G.Malbrán. Instituto de Enfermedades Infecciosas. Departamento de Micología; Argentina. Fil: Castañon-Olivares, Laura R. Universidad Nacional Autónoma de México (UNAM). Facultad de Medicina. Departamento de Microbiología y Parasitología; México. Fil: Reyes-Montes, María del Rocío. Universidad Nacional Autónoma de México (UNAM). Facultad de Medicina. Departamento de Microbiología y Parasitología; México. Coccidioides immitis and C. posadasii cause coccidioidomycosis, a disease that is endemic to North and South America, but for Central America, the incidence of coccidioidomycosis has not been clearly established. Several studies suggest genetic variability in these fungi; however, little definitive information has been discovered about the variability of Coccidioides fungi in Mexico (MX) and Argentina (AR). Thus, the goals for this work were to study 32 Coccidioides spp. isolates from MX and AR, identify the species of these Coccidioides spp. isolates, analyse their phenotypic variability, examine their genetic variability and investigate the Coccidioides reproductive system and its level of genetic differentiation.