Speckle tracking echocardiography in the indeterminate form of Chagas disease

dc.creatorCianciulli, Tomás Francisco
dc.creatorAlbarracín, Gerardo Ariel
dc.creatorNapoli Llobera, Mariano
dc.creatorPrado, Nilda Graciela
dc.creatorSaccheri, María Cristina
dc.creatorHernández Vásquez, Yolanda María
dc.creatorMéndez, Ricardo José
dc.creatorBeck, Martín Alejandro
dc.creatorBaez, Karina Giselle
dc.creatorBalletti, Lorena Romina
dc.date2020-11-26T15:41:55Z
dc.date2020-11-26T15:41:55Z
dc.date2020-11-03
dc.date.accessioned2023-08-29T20:07:17Z
dc.date.available2023-08-29T20:07:17Z
dc.identifierhttp://sgc.anlis.gob.ar/handle/123456789/1744
dc.identifier10.1111/echo.14917
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8519585
dc.descriptionFil: Cianciulli, Tomás Francisco. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Albarracín, Gerardo Ariel. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Napoli Llobera, Mariano. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Prado, Nilda Graciela. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.
dc.descriptionFil: Saccheri, María Cristina. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Hernández Vásquez, Yolanda María. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.
dc.descriptionFil: Méndez, Ricardo José. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Beck, Martín Alejandro. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Baez, Karina Giselle. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionFil: Balletti, Lorena Romina. Hospital of the Government of the City of Buenos Aires "Dr. Cosme Argerich". Division of Cardiology. Echocardiography Laboratory; Argentina.
dc.descriptionBackground: Chagas disease is one of the most common diseases in Latin-America, and cardiac involvement is a significant cause of death. Assessment of myocardial strain may detect early myocardial damage. Objectives: To determine differences in longitudinal strain using speckle tracking to assess regional and global left ventricular function in patients with the indeterminate form of Chagas disease, in comparison with a control group. Methods: This is a retrospective matched case-control study, conducted in a single center. We evaluated 45 adult patients with Chagas disease, diagnosed with 2 serological methods, without evidence of cardiac involvement, who were compared with 45 healthy control subjects, who were sex- and age-matched. All patients underwent Doppler echocardiography and longitudinal strain with speckle tracking. Results: Median age was 59 years, and 60% were female. Echocardiographic parameters were similar in patients with Chagas and control subjects. In patients with Chagas, global strain differed significantly from that of control subjects (-17 vs -20.3, P < .001). Segmental strain showed 7 abnormal segments in patients with Chagas (P < .05). Conclusions: In patients with the indeterminate form of Chagas disease, global and segmental longitudinal peak systolic strain is reduced compared with healthy subjects, thus suggesting that it could be a sensitive technique to detect early myocardial damage. These findings could provide useful information regarding the pathophysiology of cardiac involvement and understand whether they might have prognostic usefulness or help develop strategies to modify the course and prognosis of patients with Chagas disease. A longitudinal prospective study would be necessary to validate our findings.
dc.languageen
dc.publisherWiley
dc.publisherWiley Periodicals
dc.publisherInternational Society of Cardiovascular Ultrasound
dc.relation#PLACEHOLDER_PARENT_METADATA_VALUE#
dc.relationdatasets
dc.relationEchocardiography (Mount Kisco, N.Y.)
dc.rightsnone
dc.sourceEchocardiography 2020
dc.subjectEnfermedad de Chagas
dc.subjectEcocardiografía
dc.subjectMiocardio
dc.subjectAmérica Latina
dc.subjectGrupos Control
dc.subjectEcocardiografía Doppler
dc.titleSpeckle tracking echocardiography in the indeterminate form of Chagas disease
dc.typeArtículo


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