Fil: Cormick, Gabriela. Department of Mother and Child Health Research, Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires; Argentina.Fil: Ciganda, Alvaro. Unidad de Investigación Clínica y Epidemiológica Montevideo; Uruguay.Fil: Cafferata, Maria Luisa. Unidad de Investigación Clínica y Epidemiológica Montevideo; Uruguay.Fil: Sosa-Estani, Sergio. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Parasitología; Argentina.Fil: Buekens, Pierre. School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA; Estados Unidos.Fil: Belizán, José M. Department of Mother and Child Health Research, Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires; Argentina.Fil: Althabe, Fernando. Department of Mother and Child Health Research, Institute for Clinical Effectiveness and Health Policy (IECS), Buenos Aires, Argentina.Diagnosis of congenital Chagas disease occurs at 9 months of age, making effective treatment challenging due to loss to follow-up. Mobile health (mHealth) has been utilized to improve communication and treatment adherence in many chronic diseases, although no studies of mHealth in Trypanosoma cruzi-infected individuals have been conducted. Text message interventions, a subset of mHealth, has shown to improve appointment attendance and is relatively simple to set up, thus making it an ideal mechanism to facilitate communication with individuals in low-resource settings.