info:eu-repo/semantics/article
Relación entre los niveles de colinesterasa y los grupos sanguíneos ABO y Rh
Relationship between cholinesterase levels and blood groups ABO and Rh
Autor
Carmona Fonseca, Jaime
Institución
Resumen
RESUMEN: Antecedentes: se postula que las embarazadas Rh-negativo tienen actividad de colinesterasa plasmática significativamente menor que las Rh-positivo, aunque otros no encuentran tal relación; además, se dice que tal asociación no aparece en no grávidas, ni en hombres. Objetivo: conocer la relación entre grupos sanguíneos ABO-Rh con los niveles de colinesterasas eritrocitaria y plasmática en población general, por sexos, y en gestantes. Metodología: diseño descriptivo, transversal, prospectivo, con muestras de población laboral adulta, no expuesta a plaguicidas inhibidores de colinesterasa (PIC), afiliada al Seguro Social y situada en el valle de Aburrá y en el cercano oriente antioqueño (Oriente), departamento de Antioquia, Colombia. Se midieron colinesterasas eritrocitarias y plasmáticas con cinco técnicas diferentes y se fenotipificaron los grupos ABO-Rh con sueros comerciales. Resultados: en la enzima eritrocitaria, siempre el valor menor corresponde al grupo B y al Rhnegativo y el mayor valor al grupo AB y al Rh-positivo; esta regularidad no se observa en la enzima plasmática; sin embargo, las enzimas eritrocitaria, plasmática y en sangre total no muestran diferencia significativa por grupo ABO ni factor Rh dentro de ningún estrato región-sexo. En este estudio, todas las embarazadas fueron Rh-positivo y no se pudo evaluar la relación entre colinesterasa y grupo Rh en ellas. Conclusión: a) no encontramos asociación entre los grupos sanguíneos ABO y Rh con el nivel de ninguna clase de colinesterasa en no gestantes, en hombres y en población general; b) no pudimos evaluar la relación entre colinesterasa y el Rh de las gestantes. ABSTRACT: Background: it is postulated that Rh negative pregnant women have significantly less plasma cholinesterase activity than the Rh positive, although others have not found this relationship. In addition, such association is not seen in non-pregnant women or in men. Objective: to find the relationship among ABO-Rh blood groups and the levels of erythrocytes and plasma cholinesterase, in the general population according to gender as well as in pregnant women. Methodology: descriptive, cross-sectional and prospective design. Samples from adult working population (18-59 years) were taken, they had not been previously exposed to inhibiting cholinesterase pesticides (ICP) and worked in companies affiliated to the Social Security, located in the Valle de Aburrá and the Near East of Antioquia, Colombia. Erythrocyte and plasma cholinesterase were measured by five different methods and the commercial serums were used to identify the phenotypes ABO and Rh. Results: the smallest values of the erythrocytes enzyme always corresponded to group B – negative Rh and the greatest values to group AB - positive Rh. This regularity was not observed in the plasma enzyme, however, the erythrocytes, plasma and total blood enzymes did not show significant difference according to neither group ABO or Rh factor within any layer region-gender. In this study, all the pregnant women were positive Rh and it was not possible to be evaluated the relation between cholinesterase and Rh group in them. Conclusion: a) we did not find any association between blood group ABO and Rh with any cholinesterase level in non-pregnant women, in men and in the general population. b) We could not assess the relationship between cholinesterase and Rh in pregnant women. COL0047449