dc.creatorCienfuegos Gallet, Astrid Vanessa
dc.creatorChen, Liang
dc.creatorKreiswirth, Barry
dc.creatorJimenes Quiceno, Judy Natalia
dc.date2021-07-04T14:00:51Z
dc.date2021-07-04T14:00:51Z
dc.date2017
dc.date.accessioned2023-08-28T19:39:17Z
dc.date.available2023-08-28T19:39:17Z
dc.identifier0066-4804
dc.identifierhttp://hdl.handle.net/10495/20639
dc.identifier10.1128/AAC.00404-17
dc.identifier1098-6596
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8465833
dc.descriptionABSTRACT : Here we describe the spread of colistin resistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae in Medellín, Colombia. Among 32 isolates collected between 2012 and 2014, 24 showed genetic alterations in mgrB. Nineteen isolates belonged to sequence type 512 (ST512) (or its single locus variant [SLV]) and harbored an 8.1-kb hsdMSR insertion corresponding to ISKpn25, indicating a clonal expansion of the resistant strain. The insertion region showed 100% identity to several plasmids, suggesting that the colistin resistance is mediated by chromosomal integration of plasmid DNA.
dc.descriptionCOL0126131
dc.format5
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.publisherGrupo de Investigación en Microbiología Básica y Aplicada-Microba
dc.publisherWashington, Estados Unidos
dc.relationAntimicrob. agents chemother
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://creativecommons.org/licenses/by/2.5/co/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.rightshttps://creativecommons.org/licenses/by/4.0/
dc.subjectKlebsiella pneumoniae
dc.subjectColistina
dc.subjectColistin
dc.subjectEnterobacteriaceae Resistentes a los Carbapenémicos
dc.subjectCarbapenem-Resistant Enterobacteriaceae
dc.titleColistin resistance in carbapenem resistant klebsiella pneumoniae mediated by chromosomal integration of plasmid DNA
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typehttp://purl.org/coar/resource_type/c_2df8fbb1
dc.typehttps://purl.org/redcol/resource_type/ART
dc.typeArtículo de investigación


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