Articulo
Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Due to Ovariectomy in Skeletally Mature Mice.
J. Biol. Chem.
Registro en:
15090007
15090007
Autor
Dudakovic, A.
Camilleri, E. T.
Riester, S. M.
Paradise, C. R.
Gluscevic, M.
O'Toole, T. M.
Thaler, R.
Evans, J. M.
Yan, H.
Subramaniam, M.
Hawse, J. R.
Stein, G. S.
Montecino, M. A.
McGee-Lawrence, M. E.
Westendorf, J. J.
van Wijnen, A. J.
Institución
Resumen
Perturbations in skeletal development and bone degeneration may result in reduced bone mass and quality, leading to greater fracture risk. Bone loss is mitigated by bone protective therapies, but there is a clinical need for new bone-anabolic agents. Prev FONDAP FONDAP