Articulo
Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations
Brain Res
Autor
Mollereau, B.
Roussel, B. D.
Chevet, E.
Sedru, M.
Van den, Brink D.
Bailly-Maitre, B.
Palladino, F.
Medinas, D. B.
Domingos, P. M.
Hunot, S.
Chandran, S.
Rzechorzek, N. M.
Birman, S.
Baron, T.
Vivien, D.
Duarte, C. B.
Ryoo, H. D.
Crowder
Institución
Resumen
In neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of cellu FONDAP FONDAP