Articulo
Dexamethasone and monophosphoryl lipid a-modulated dendritic cells promote antigen-specific tolerogenic properties on naive and memory cd4+ t cells.
Frontiers in Immunology
Registro en:
1140553
1140553
Autor
Maggi, Jaxaira
Schinnerling, Katina
Pesce, Barbara
Hilkens, Catharien M
Catalán, Diego Francisco
Aguillón-Gutiérrez, Juan Carlos
Institución
Resumen
Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs (tDCs)] to exert immunomodulato Regular FONDECYT FONDECYT