Articulo
Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis through EGFR transactivation
Frontiers in Cellular Neuroscience
Autor
Reinchisi, G.
Parada, M.
Lois, L.
Oyanedel, C.
Shaughnessy, R.
González, A.
Palma, V.
Institución
Resumen
Sonic Hedgehog (Shh/GLI) and EGFR signaling pathways modulate Neural Stem Cell (NSC) proliferation. How these signals cooperate is therefore critical for understanding normal brain development and function. Here we report a novel acute effect of Shh signa FONDAP FONDAP