Articulo
Release of Acetylcholinesterase (AChE) from β-Amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
Chem. Biol. Interact.
Registro en:
13980001
13980001
Autor
Dinamarca, M.
Arrázola, M.
Toledo, E.
Cerpa, W.
Hancke, J.
Inestrosa, N. C.
Institución
Resumen
The major protein constituent of amyloid deposits in Alzheimer's disease (AD) is the amyloid-beta-peptide (Abeta). Amyloid deposits contain "chaperone molecules" which play critical roles in amyloid formation and toxicity. In the present work, we test an FONDAP FONDAP