Articulo
Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons
Molecular and Cellular Neurosciences
Registro en:
15090007
15090007
Autor
Henriquez, B.
Bustos, F.
Aguilar, R.
Becerra, A.
imon, F.
Montecino, M.
van Zundert, B.
Institución
Resumen
Polycomb Repressive Complex 2 (PRC2) mediates transcriptional silencing by catalyzing histone H3 lysine 27 trimethylation (H3K27me3), but its role in the maturation of postmitotic mammalian neurons remains largely unknown. We report that the PRC2 paralogs FONDAP FONDAP