Articulo
Innexins: Expression, Regulation, and Functions
FRONTIERS IN PHYSIOLOGY
Registro en:
1150291
1150291
Autor
Guiza, Juan
Barria, Iván
Sáez-Carreño, Juan Carlos
Vega, José L
Institución
Resumen
The innexin (Inx) proteins form gap junction channels and non-junctional channels (named hemichannels) in invertebrates. These channels participate in cellular communication playing a relevant role in several physiological processes. Pioneer studies conducted mainly in worms and flies have shown that innexins participate in embryo development and behavior. However, recent studies have elucidated new functions of innexins in Arthropoda, Nematoda, Annelida, and Cnidaria, such as immune response, and apoptosis. This review describes emerging data of possible new roles of innexins and summarizes the data available to date. Regular 2015 FONDECYT FONDECYT