Ponencia
Involvement of HDL receptor SR-BI-mediated vitamin E uptake in murine neural tube closure.
Autor
Santander, Nicolás
Pérez, Druso
Echeverria, Guadalupe
Mendoza, Camila
Cautivo, K
Rigotti, Attilio
Busso-Perkins, Dolores
Institución
Resumen
SR-BI, the main HDL receptor, mediates the cellular uptake of cholesterol
and vitamin E. SR-BI is present in trophoblast giants cells (TGC) during
early pregnancy and 50% SR-BI-deficient (SR-BI / ) embryos die due to
defective neural tube closure (NTD).
O FONDECYT FONDECYT