Articulo
An Agonistic mAb Directed to the TrkC Receptor Juxtamembrane Region Defines a Trophic Hot Spot and Interactions with p75 Coreceptors
Dev Neurobiol.
Registro en:
13980001
13980001
Autor
Guillemard, V.
Ivanisevic, L.
Garcia, A. G.
Scholten, V.
Lazo, O. M.
Bronfman, F. C.
Saragovi, H. U.
Institución
Resumen
The D5 domain of TrkC receptors is a docking site for Neurotrophin-3 (NT-3), but other domains may be relevant for function or harmonizing signals with p75(NTR) coreceptors. We report a monoclonal antibody (mAb) 2B7 targeting the juxtamembrane domain of T FONDAP FONDAP