Articulo
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury
eLife
Autor
Calvo, Margarita
Ricahrds, Natalie
Schmid, Annina B.
Barroso, Alejandro
Zhu, Lan
Ivulic, Dinka
Zhu, Ning
Anwandter, Philipp
Manzoor, A. Bhat
Court, Felipe A.
McMahom, Sephen B.
Bennet, David L. H.
Institución
Resumen
Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of shaker-type-potassium channels (Kv1 chann FONDAP FONDAP